Optimal release programs for dengue prevention using aedes aegypti mosquitoes transinfected with wmel or wmelpop wolbachia strains
Artículo de revista
2021-03
AIMS Press
In this paper, we propose a dengue transmission model of SIR(S)-SI type that accounts
for two sex-structured mosquito populations: the wild mosquitoes (males and females that are Wol-
bachia-free), and those deliberately infected with either wMel or wMelPop strain of Wolbachia. This
epidemiological model has four possible outcomes: with or without Wolbachia and with or without
dengue. To reach the desired outcome, with Wolbachia and without dengue, we employ the dynamic
optimization approach and then design optimal programs for releasing Wolbachia-carrying male and
female mosquitoes. Our discussion is focused on advantages and drawbacks of two Wolbachia strains,
wMelPop and wMel, that are recommended for dengue prevention and control. On the one hand, the
wMel strain guarantees a faster population replacement, ensures durable Wolbachia persistence in the
wild mosquito population, and requiters fewer releases. On the other hand, the wMelPop strain displays
better results for averting dengue infections in the human population
- Articulos [993]
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Título: Optimal release programs for dengue prevention using Aedes aegypti mosquitoes transinfected with wMel or wMelPop Wolbachia strains.pdf
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Título: Optimal release programs for dengue prevention using Aedes aegypti mosquitoes transinfected with wMel or wMelPop Wolbachia strains.pdf
Tamaño: 2.856Mb


