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dc.contributor.authorSepulveda Salcedo, Lilian Sofiaspa
dc.contributor.authorVasilieva, Olgaspa
dc.contributor.authorSvinin, Mikhailspa
dc.description.abstractIn this paper, we reflect upon control intervention practices habitually exerted by healthcare authorities in tropical areas that suffer from incidental outbreaks of dengue fever, in particular, the city of Cali, Colombia. Such control interventions, principally based on the insecticide spraying, are carried out sporadically in order to overcome an ongoing epidemic or at least to reduce its size. It is worth pointing out that control actions of this type do not usually account for sufficient budget because epidemic outbreaks are difficult to predict. In practical terms, these occasional control interventions are performed by spraying, as quickly as possible, all existing stock of insecticide (regardless of its lethality) and employing all available manpower. The goal of this paper is to design better strategies for insecticide-based control actions, which are capable of preventing more human infections at no additional cost, and to reveal the obsolescence of current vector eradication practices. Our approach relies on dynamic optimization, where the number of averted human infections is maximized under budget constraint and subject to a simple dengue transmission model amended with one control variable that stands for the insecticide spraying. As a result, we obtain structurally robust control intervention policies that demonstrate better performance and higher resilience to possible budget limitations than traditional modus operandieng
dc.format.extent28 páginasspa
dc.rightsDerechos reservados - Wiley, 2020spa
dc.titleOptimal control of dengue epidemic outbreaks under limited resourceseng
dc.typeArtículo de revistaspa
dc.subject.armarcControl vectorialspa
dc.subject.armarcVector controleng
dc.contributor.corporatenameStudies in Applied Mathematicseng
dc.relation.citationeditionVolumen 144, número 2 (2020)spa
dc.relation.citationissueNúmero 2spa
dc.relation.citationvolumeVolumen 144spa
dc.relation.citesSepulveda Salcedo, L.S., Vasilieva, O., Svinin M. (2020). Optimal control of dengue epidemic outbreaks under limited resources. Studies in Applied Mathematics. (Vol. 144 (2), pp. 185-212.
dc.relation.ispartofjournalStudies in Applied Mathematicseng
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dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)spa
dc.subject.proposalDengue outbreakseng
dc.subject.proposalInsecticide based vector controleng
dc.subject.proposalIsoperimetric constrainteng
dc.subject.proposalOptimal controleng
dc.subject.proposalRoss-Macdonald modeleng

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